Oxygenation Targets and Outcomes in Premature Infants Oxygenation Targets and...
Many premature infants experience respiratory failure and receive supplemental oxygen for prolonged periods. While this therapy is crucial for their survival, it can be associated with complications...
View ArticleEffects of Targeting Higher vs Lower Arterial Oxygen Saturations on Death or...
ImportanceThe goal of oxygen therapy is to deliver sufficient oxygen to the tissues while minimizing oxygen toxicity and oxidative stress. It remains uncertain what values of arterial oxygen...
View ArticleHead Lice
Head lice are tiny insects that infest the hair on your head, as well as the eyebrows and eyelashes. Tiny louse eggs called nits are tightly attached to individual hairs and live close to the scalp,...
View ArticleThe Evolving Role and Value of Libraries and Librarians in Health Care
Changes in medical information and technology are revolutionizing health care. As clinicians try to incorporate research into practice through comparative effectiveness research and decision support,...
View ArticleHigh-tech Care Can Save Lives—But It Also May Create Incentives That Result...
In a news story about the care provided to premature infants in neonatal intensive care units (NICUs), reporter Alex Halperin illuminated the miracles and unintended consequences of health care...
View ArticleEffect of Depth and Duration of Cooling on Deaths in the NICU Among Neonates...
ImportanceHypothermia at 33.5°C for 72 hours for neonatal hypoxic ischemic encephalopathy reduces death or disability to 44% to 55%; longer cooling and deeper cooling are neuroprotective in animal...
View ArticleDepth and Duration of Cooling for Perinatal Asphyxial Encephalopathy
This Editorial encourages continuing efforts to improve the efficacy of treatment for perinatal asphyxial encephalopathy.
View ArticleProtocolized Sedation vs Usual Care in Pediatric Patients Mechanically...
ImportanceProtocolized sedation improves clinical outcomes in critically ill adults, but its effect in children is unknown.ObjectiveTo determine whether critically ill children managed with a...
View ArticleProtocolized Sedation in Critically Ill Children
Light sedation or no sedation has become the therapeutic goal in critically ill adults. Large randomized trials and systematic reviews have demonstrated that this goal is feasible, safe, and...
View ArticleIsotonic vs Hypotonic Intravenous Fluids for Hospitalized Children
This Clinical Evidence Synopsis summarizes a recent Cochrane Review comparing the risk of hyponatraemia with isotonic vs hypotonic intravenous fluid for maintenance hydration in children.
View ArticleGut Dysbiosis and Necrotizing Enterocolitis
This Medical News feature explores the association between dysbiosis in a preterm infant’s gut microbiome and the subsequent development of necrotizing enterocolitis.
View Article
